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Cancer Therapy Evaluation Program (CTEP)
Last Updated: 04/03/16

Adult Brain Tumor Consortium

The Adult Brain Tumor Consortium (ABTC) is a multi-institutional consortium that is supported through a UM1 Cooperative Agreement from the NCI. The consortium performs innovative, multidisciplinary Phase 1 - 2 clinical trials that focus predominantly on adult patients with grade IV gliomas (glioblastoma multiforme). ABTC's objectives are:

  • to perform multidisciplinary clinical trials using surgery, radiation and systemic therapies

  • to combine targeted agents in appropriate combination regimens

  • to incorporate pharmacokinetic and pharmacodynamic endpoints as appropriate into clinical trials testing novel agents

  • to evaluate novel imaging endpoints in clinical trials

  • to foster collaborations with other researchers in the field, including the NCI-funded brain tumor SPORES and the National Clinical Trials Network (NCTN)

The ABTC consists of investigators at premier institutions across the United States. ABTC has demonstrated that clinical trials are not only possible in this challenging tumor type, but represent the best hope for making further progress against this devastating disease.