Investigator Resources

Guidelines / Policies

• Revised! NCI National Clinical Trials Network (NCTN) Program Guidelines (PDF)
  • Brief Overview of Key Information for FOAs Under the NCTN Program (PDF)
  • Links to Funding Opportunity Announcements for NCTN Program are below:

  NCTN Program Key Component	Funding Opportunity Announcement (FOA)
  Network Group Operations Centers	RFA-CA-12-010 (U10)
  Network Group Statistics & Data Management Centers	RFA-CA-12-011 (U10)
  Network Group Integrated Translational Science Centers	RFA-CA-12-012 (U10)
  Network Lead Academic Participating Sites	RFA-CA-12-013 (U10)
  Network Radiotherapy & Imaging Core Services Centers	RFA-CA-12-014 (U24)
  Canadian Collaborating Clinical Trials Network	RFA-CA-12-504 (Limited Competition U10)

  • Frequently Asked Questions - December 15, 2012 for NCTN Program (PDF)
    • Contact NCI/DCTD by email at: ncictepanalyst@mail.nih.gov with any questions on the FOAs prior to the application deadlines

• Cooperative Group Guidelines (PDF)
  Note: These Guidelines are expiring. New applicants, please see instead "NCI NCTN Program Guidelines" above.
• Guidelines for Multicenter Collaborations
• Guidelines for Monitoring of Clinical Trials for Cooperative Groups, CCOP Research Bases, and the Cancer Trials Support Unit (CTSU)
• NCI Clinical Trials Cooperative Group Program Guidelines for Development, Conduct and Analysis of Clinical Trials with International Collaborating Institutions (PDF)
• CTEP Conflict of Interest Policy for Cooperative Group Phase 3 Trials (PDF)

Early Therapeutics Clinical Trials Network (ET-CTN)

• ET-CTN Program Guidelines
• RFA-CA-13-006 TABLE TEMPLATES
• FOA for the ET-CTN
• ET-CTN Informatics and Update Meeting - Presentation 1
• ET-CTN Informatics and Update Meeting - Presentation 2
• ET-CTN Informatics and Update Meeting - Presentation 3
• ET-CTN Informatics and Update Meeting - Presentation 4
• ET-CTN Informatics and Update Meeting - Presentation 5
• ET-CTN Informatics and Update Meeting - Presentation 6

Investigator Registration Packet

• Investigator Registration Packet

Investigator's Handbook

• Investigator's Handbook
• CTEP's Review Types and Decision Tree (MS Word)
• CTEP Review Flow for Cooperative Group Phase 3 Trials

Biomarker Resources

Cancer / Clinical Trial Information

• Cancer Information Service (CIS)
• NCI's PDQ® database of cancer clinical trials
  1-800-4-CANCER
• ClinicalTrials.gov
• Search for Clinical Trials
• Food and Drug Administration Amendments Act of 2007 (FDAAA)

Career Development Opportunities

Childhood Cancer Resources

• Patient/Caregiver Ad Hoc Education Template
• Childhood Cancer Resources

CTSU / Research Organizations

• Clinical Trials Cooperative Group Program
• Cancer Trials Support Unit (CTSU)
• Community Clinical Oncology Program (CCOP) in the Division of Cancer Prevention
• The North American Breast Cancer Group (NABCG)
• Gynecologic Cancer Intergroup (GCIG)

CIRB / Study Participant Protections

• Central IRB (CIRB) Initiative
• NIH Protecting Human Research Participants Course
• Office for Human Research Protections (OHRP) - IRB Registration and Assurance Filing
• OHRP's IRB Guidebook

Funding Opportunities

• PA-06-338: R21 FOA Component of PA-04-157
• NOT-CA-06-023: Notice of Availability of Administrative Supplements for Studies of Cancer in HIV/AIDS

Funding Links

• Grants.gov - the Source to Find and Apply for Federal Grants
• NCI Extramural Funding Opportunities
  • Program Announcements
  • Request for Applications
  • Funding Opportunities/Notices Search

• Office of Acquisitions
• Small Business Research Funding Opportunities
• Symptom Management and Palliative Care Funding Opportunities

Data Sharing Links

• Model Cooperative Group Data Sharing Policy (MS Word)
• Model Cooperative Group Data Sharing Policy (PDF)
• Each Cooperative Group has a data sharing policy modeled after the data sharing template. For specific data requests contact the appropriate Cooperative Group. (Click here for Cooperative Group links)

Young Investigator Meeting - ASCO 2011

• Young Investigator Meeting (MS PowerPoint)
• Visiting Physician Externship (MS PowerPoint)
• Letters of Intent (LOI) Basics (MS PowerPoint)
• IND LOI Review and Approval Process (MS PowerPoint)