Brain Metastases in Breast Cancer Workshop

Ritz Carlton, Arlington, VA 22202
Sunday-Monday, March 1-2, 2009

Agenda

Day 1: Sunday, March 1, 2009

Part I: Introductions and Overview

Subject	Speaker	Affiliation
Welcome	Nancy Lin and Minesh Mehta	Dana Farber Cancer Institute and U. of Wisconsin
Introduction	Minesh Mehta and Nancy Lin	Dana Farber Cancer Institute and U. of Wisconsin
General Overview	Eric Winer	Dana Farber Cancer Institute

Part II: Presentations

Pre-Clinical Data

Subject	Speaker	Affiliation
Preclinical data overview and brain permeable compounds	Pat Steeg and Quentin Smith	NCI and Texas Tech
Signatures for brain relapse	Sunil Badve	Indiana University

 

Clinical Data and Lessons Learned

Subject	Speaker	Affiliation
ENRICH trial	John Suh	Cleveland Clinic
Motexafin trial	Minesh Mehta	U. Wisconsin
Lapatinib trials	Nancy Lin	Dana Farber Cancer Institute
Epothilone trials	David Peereboom	Cleveland Clinic
Angiogenesis inhibitors for brain tumors/mets	April Eichler	Mass General Hospital

Day 2: Monday, March 2, 2009

Part III: Presentations

Overview of Trial Groups/Consortia

Subject	Speaker	Affiliation
Rapid early stage trials: Unique designs	Morris Groves	MD Anderson
TBCRC	Eric Winer	Dana Farber Cancer Institute
P2C	Jamie Zwiebel	NCI
RTOG	Walter Curran	Emory
Opportunities and resources for molecular imaging in clinical trials	Lalitha Shakar	NCI
Novel imaging methods	Christina Tsien	Harvard Medical School and Massachusetts General Hospital

 

Surgery and Radiosurgery

Subject	Speaker	Affiliation
Surgical considerations	Fred Lang	MD Anderson
Radiosurgery (incl multiple lesions) & necrosis	Ajay Bhatnagar	Cancer Treatment Services Arizona
Role of PCI	Elizabeth Gore	Medical College of Wisconsin
Discussion	All

 

Surrogate endpoints

Subject	Speaker	Affiliation
Cognitive evaluation; neuroprotective strategies	Minesh Mehta	U. of Wisconsin
Neuro-psych testing in multicenter studies	Jeffrey Scott Wefel	MD Anderson