U.S. National Institutes of Health
Last Updated: 08/11/09

Brain Metastases in Breast Cancer Workshop

Ritz Carlton, Arlington, VA 22202
Sunday-Monday, March 1-2, 2009

Agenda

Day 1: Sunday, March 1, 2009
Part I: Introductions and Overview Speaker Affiliation
Welcome Nancy Lin and Minesh Mehta Dana Farber Cancer Institute and U. of Wisconsin
Introduction Minesh Mehta and Nancy Lin Dana Farber Cancer Institute and U. of Wisconsin
General Overview Eric Winer Dana Farber Cancer Institute
Part II: Presentations    
Pre-Clinical Data
Preclinical data overview and brain permeable compounds Pat Steeg and Quentin Smith NCI and Texas Tech
Signatures for brain relapse Sunil Badve Indiana University
Clinical Data and Lessons Learned
ENRICH trial John Suh Cleveland Clinic
Motexafin trial Minesh Mehta U. Wisconsin
Lapatinib trials Nancy Lin Dana Farber Cancer Institute
Epothilone trials David Peereboom Cleveland Clinic
Angiogenesis inhibitors for brain tumors/mets April Eichler Mass General Hospital

Day 2: Monday, March 2, 2009
Part III: Presentations Speaker Affiliation
Overview of Trial Groups/Consortia
Rapid early stage trials: Unique designs Morris Groves MD Anderson
TBCRC Eric Winer Dana Farber Cancer Institute
P2C Jamie Zwiebel NCI
RTOG Walter Curran Emory
Opportunities and resources for molecular imaging in clinical trials Lalitha Shakar NCI
Novel imaging methods Christina Tsien Harvard Medical School and Massachusetts General Hospital
Surgery and Radiosurgery
Surgical considerations Fred Lang MD Anderson
Radiosurgery (incl multiple lesions) & necrosis Ajay Bhatnagar Cancer Treatment Services Arizona
Role of PCI Elizabeth Gore Medical College of Wisconsin
Discussion All  
Surrogate endpoints
Cognitive evaluation; neuroprotective strategies Minesh Mehta U. of Wisconsin
Neuro-psych testing in multicenter studies Jeffrey Scott Wefel MD Anderson