Adult Brain Tumor Consortium
The Adult Brain Tumor Consortium (ABTC) is a multi-institutional consortium that is supported through a UM1 Cooperative Agreement from the NCI. The consortium performs innovative, multidisciplinary Phase 1 - 2 clinical trials that focus predominantly on adult patients with grade IV gliomas (glioblastoma multiforme). ABTC's objectives are:
to perform multidisciplinary clinical trials using surgery, radiation and systemic therapies
to combine targeted agents in appropriate combination regimens
to incorporate pharmacokinetic and pharmacodynamic endpoints as appropriate into clinical trials testing novel agents
to evaluate novel imaging endpoints in clinical trials
to foster collaborations with other researchers in the field, including the NCI-funded brain tumor SPORES and the National Clinical Trials Network (NCTN)
The ABTC consists of investigators at premier institutions across the United States. ABTC has demonstrated that clinical trials are not only possible in this challenging tumor type, but represent the best hope for making further progress against this devastating disease.