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Last Updated: 11/10/16

Charles Kunos, MD, PhD, Medical Officer

Charles Kunos, MD, PhD, Medical Officer

Dr. Charles Kunos joined CTEP in 2016. He received his MD and PhD from Case Western Reserve University School of Medicine. Subsequently, he served as the Clinical Director of the Gynecologic, Pediatric, and Musculoskeletal Radiation Therapy service lines in the Department of Radiation Oncology at University Hospitals of Cleveland and Assistant Professor in the Department of Radiation Oncology at Case Western Reserve University. In this capacity, he was responsible for delivering teletherapy in the clinic and brachytherapy in the clinic and the operating room. He developed skills in helical tomotherapy, gamma knife radiosurgery, and Cyberknife stereotactic body radiosurgery. In addition, he was the Gynecologic Oncology Group liaison for Radiation Medicine, serving on multiple committees, including the Developmental Therapeutics Committee of the NRG Oncology cooperative group, serving as co-chair of the phase I committee between January 2012 and February 2015. He has served on the National Cancer Institute Uterine Task Force since 2012.

Dr. Kunos was responsible for overseeing a preclinical laboratory focused on the science of ribonucleotide reductase, utilizing a NCI-Cancer Therapy Evaluation Program (CTEP)-Case Western Reserve University agreement to conduct preclinical studies of the ribonucleotide reductase inhibitor Triapine in uterine cervix cancer. He subsequently was the principal investigator on NCI-sponsored Phase I and Phase II clinical trials of Triapine radiochemotherapy in uterine cervix cancer patients, which demonstrated high response rates that are being further evaluated in CTEP-sponsored trials.

More recently, he served as the Medical Director of Radiation Oncology at Summa Health (Akron, Ohio) where he treated patients with brachytherapy and stereotactic radiosurgery. He received certification and medical expertise in Vero radiosurgery and Vero dynamic tumor tracking, and radiation safety administration of the Vero platform and led the clinical development of the first Vero radiosurgery program in a community hospital setting in the world.

Contact Information:
National Cancer Institute
9609 Medical Center Dr., MSC 9739
For USPS: Bethesda, MD 20892-9739
For Express and Courier: Rockville, MD 20850
Phone: 240-276-6939
Fax: 240-276-7894
E-mail: charles.kunos@nih.gov

About the Branch Chief

James Zwiebel, MD James Zwiebel received the MD degree from the Mount Sinai School of Medicine, where he also completed his residency training in internal medicine. Following a clinical fellowship in hematology and oncology at the George Washington University Medical Center and research fellowships at both the National Cancer Institute and the National Heart Lung and Blood Institute, he continued his laboratory work on cancer gene therapy as a member of the faculty at Lombardi Cancer Center of the Georgetown University Medical Center, where he also practiced hematology and oncology. More…