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Last Updated: 07/12/17

NCI Early Drug Development Opportunity Program (EDDOP)

Under the NCI Early Drug Development Opportunity Program (EDDOP), any NCI-designated Cancer Center (NCI-CC) not affiliated with the ETCTN may still be able to participate in ETCTN trials as a lead clinical site or as a participating site.

1. Leading an ETCTN Trial

Investigators from non-ETCTN NCI-designated Cancer Centers (NCI-CCs) are invited to submit Letters of Intent (LOIs) to conduct clinical trials with CTEP IND agents. If the LOI is approved by the CTEP Protocol Review Committee, the investigator could receive full ETCTN support for the clinical trial, including the following benefits:

  • accrual across ETCTN sites
  • access to the Central Institutional Review Board (CIRB)
  • registration and data management support
  • funds for salary reimbursement and accrual at the investigator’s home institution through a supplement to the NCI-CC’s P30 grant

Important Update to Process (May 5, 2016): Before submitting a an LOI through the EDDOP, contact the IDB Monitor(s) for the intended CTEP agent(s) to schedule a preliminary conference. EDDOP LOIs submitted without holding a preliminary conference will be refused. Please see CTEP Agents and Active Agreements for the current list of IDB Monitors.

2. Participating in ETCTN Trials Led by ETCTN Sites

Non-ETCTN NCI-designated Cancer Centers will be also able to compete for administrative supplements to enroll patients on select ETCTN phase 2 trials.

3. Current EDDOP Sites

These sites are currently participating in the EDDOP program.
University of Alabama at Birmingham Cancer Center
University of Arizona Medical Center-University Campus
University of Arizona Cancer Center-North Campus
Northwestern University
University of Chicago Comprehensive Cancer Center
UC Comprehensive Cancer Center at Silver Cross
University of Chicago Medicine-Orland Park
University of Kansas Cancer Center
University of Kansas Hospital-Westwood Cancer Center
University of Kansas Clinical Research Center
University of Michigan Comprehensive Cancer Center
University of Nebraska Medical Center
Dartmouth-Hitchcock Medical Center/Norris Cotton Cancer Center
Laura and Isaac Perlmutter Cancer Center at NYU Langone
Montefiore Medical Center - Moses Campus
Montefiore Medical Center-Weiler Hospital
Montefiore Medical Center-Einstein Campus
Roswell Park Cancer Institute
Fox Chase Cancer Center
UT Southwestern/Simmons Cancer Center-Dallas
UT Southwestern/Simmons Cancer Center-Fort Worth
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Ben Taub General Hospital
Huntsman Cancer Institute/University of Utah