CTEP Branches and Offices
NCI Registration and Credential Repository (RCR)
Food and Drug Administration (FDA) regulations require IND sponsors to select qualified investigators. NCI policy requires all persons participating in any NCI-sponsored clinical trial to register and renew their registration annually.
Registration is accomplished via the NCI Registration and Credential Repository (RCR).
RCR utilizes FIVE person registration types.
- Investigator (IVR) — MD, DO, or international equivalent
- Non-Physician Investigator (NPIVR) — advanced practice providers (e.g., NP or PA) or graduate level researchers (e.g., PhD)
- Associate Plus (AP) — clinical site staff (e.g., RN or CRA) with data entry access to CTSU applications (e.g., RUMS, OPEN, RAVE, TRIAD)
- Associate (A) — other clinical site staff involved in the conduct of NCI-sponsored trials
- Associate Basic (AB) — individuals (e.g., pharmaceutical company employees) with limited access to NCI-supported systems
RCR requires the following registration documents:
| Documentation Required | IVR | NPIVR | AP | A | AB |
|---|---|---|---|---|---|
| FDA Form 1572 | ✔ | ✔ | |||
| Financial Disclosure Form | ✔ | ✔ | ✔ | ||
| NCI Biosketch (education, training, employment, license, and certification) | ✔ | ✔ | ✔ | ||
| HSP/GCP training | ✔ | ✔ | ✔ | ||
| Agent Shipment Form (if applicable) | ✔ | ||||
| CV (optional) | ✔ | ✔ | ✔ |
RCR Related Links
RCR Presentations and Checklists
Introduction to CTEP’s Registration and Credential Repository (RCR)
RCR Registration Type Checklists:
RCR FAQs
How do I prepare for creating a Registration and Credential Repository (RCR) profile?
When do I have to re-register in RCR?
I have a new clinical site staff person (IVR, NPIVR, AP, or A). Where do I start?
I have my CTEP Person ID; but, I need to register as an IVR, NPIVR, or AP. What next?
I’m unable to add my Investigator to one of our clinical sites. What do I do?