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Last Updated: 02/28/23

Recent Research Spotlights

Selected CTEP Clinical Accomplishments – February 2023

Immunotherapy Combination Most Effective as Initial Treatment for BRAF+ Melanoma

Drug combination helps children with acute promyelocytic leukemia avoid conventional chemotherapy

50 Years of Cancer: Collaboration in Combating Childhood Cancer

Seeing a Promising Future for Progress against Childhood Cancer

FDA Approval of Rylaze Will Address Drug Shortage for Childhood ALL

Implementing Criteria to Expand Clinical Trial Eligibility — An Analysis of NCI Cancer Therapy Evaluation Program (CTEP)-Sponsored Protocols

For Kids with Medulloblastoma, Trial Suggests Radiation Can Be Tailored

Nivolumab-Based Combinations Improve Survival in Advanced Esophageal Cancer

COVID-19 Vaccines May Be Less Effective in Some People with Cancer

Clinical Trials and Translational Research Advisory Committee: Strategic Planning Working Group Report, Nov. 4, 2020

Brentuximab May Mean Less Radiation for Children, Teens with Hodgkin Lymphoma

Healthcast Podcast Featuring Drs. Jim Doroshow and Meg Mooney – 50 Years of Cancer: The Road to Better Treatment and Diagnostics

Blinatumomab Improves Survival in Children with Relapsed Leukemia

Trial Tests Abemaciclib As New Option for Early-Stage Breast Cancer

Some Postmenopausal Women with Breast Cancer May Forgo Chemotherapy

Study of "Exceptional Responders" Yields Clues to Cancer and Potential Treatments

Radiopharmaceuticals: Radiation Therapy Enters the Molecular Age

Results from the Molecular Analysis of the Initial Screening Phase of the NCI-MATCH Trial

Trastuzumab May Improve Survival in Women with Rare Endometrial Cancer

New Drug Regimen Cures More Children with Aggressive B-Cell Lymphoma

Responding to Coronavirus, Cancer Researchers Reimagine Clinical Trials

How Does COVID-19 Affect People with Cancer? NCCAPS Will Help Find Out

Encorafenib, Cetuximab Combination Approved for Metastatic Colorectal Cancer

At NCI, A Robust and Rapid Response to the COVID-19 Pandemic

NCI statement on clinical trials during COVID-19 pandemic

In NIH trial, selumetinib shrinks tumors, provides clinical benefit for children with NF1

Immunotherapy Drug Improves Outcomes for Some Children with Relapsed Leukemia

Surgery for Recurrent Ovarian Cancer Does Not Improve Survival

Analysis Shows Women with High Breast Cancer Recurrence Scores Benefit from Chemo

For Children with Neuroblastoma, Trial Results Highlight Continued Evolution of Treatment

Study Quantifies Impact of NCI-sponsored Trials on Clinical Cancer Care

FDA Approves Entrectinib Based on Tumor Genetics Rather Than Cancer Type

Pembrolizumab Approved for Some Patients with Advanced Esophageal Cancer

Study Tests Immunotherapy in People with Cancer and Autoimmune Diseases

Can Some Women Treated for Endometrial Cancer Forgo Radiation after Surgery?

Pediatric MATCH Study Finds More Targetable Genetic Changes than Expected

New Drugs, New Side Effects: Complications of Cancer Immunotherapy

Some Children with Liver Cancer May Need Less Chemotherapy, Study Suggests

Making Cancer Clinical Trials Available to More Patients

Treatment for Children with Leukemia Also Effective for Adolescents, Young Adults

Whole- and Partial-Breast Radiation Effective at Preventing Breast Cancer from Returning

Olaparib after Initial Treatment Delays Ovarian Cancer Progression