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Last Updated: 11/13/17

An Overview of NCI’s National Clinical Trials Network

On March 1, 2014, after several years of extensive consultation and coordination with many stakeholders, NCI transformed its longstanding Cooperative Group program into the new National Clinical Trials Network (NCTN). Guided by recommendations in a 2010 Institute of Medicine (IOM) report, the design and implementation of the NCTN incorporates feedback from Cooperative Group investigators, NCI Comprehensive Cancer Center directors, several NCI working groups, leading cancer researchers, industry representatives, and patient advocates. For a detailed review of the new NCTN and its goals please click here.

Links to 2017 Funding Opportunity Announcements for NCTN Program are below:

NCTN Program Key Component Funding Opportunity Announcement (FOA)
Network Group Operations Centers — Limited Competition RFA-CA-17-056 (U10)
Pre-Application Webinar Slide Presentation for RFA-CA-17-56 (PDF)
List of All NCTN Trials Open Between 3-1-2014 and 8-31-2017 (EXCEL)
Network Group Statistics & Data Management Centers — Limited Competition RFA-CA-17-057 (U10)
Pre-Application Webinar Slide Presentation for RFA-CA-17-57 (PDF)
Canadian Collaborating Clinical Trials Network — Limited Competition RFA-CA-17-058 (U10)
Pre-Application Webinar Slide Presentation for RFA-CA-17-58 (PDF)
Network Lead Academic Participating Sites RFA-CA-17-059 (UG1)
Pre-Application Webinar Slide Presentation for RFA-CA-17-059 (PDF)
List of All NCTN Adult and Network AYA Trials Open Between 3-1-2014 and 8-31-2017 (EXCEL)
Change to Application Package (RFA-CA-17-059) to Allow 6-Year Budget at NOT-CA-18-017
Network Radiotherapy & Imaging Core Services Centers — Limited Competition RFA-CA-17-060 (U24)
Pre-Application Webinar Slide Presentation for RFA-CA-17-060 (PDF)
Network Group Integrated Translational Science Centers RFA-CA-17-061 (UG1)
Pre-Application Webinar Slide Presentation for RFA-CA-17-061 (PDF)
Change to Application Package (RFA-CA-17-061) to Allow 6-Year Budget at NOT-CA-18-017

DCTD is collaborating with the Center for Cancer Genomics on the Clinical Trial Sequencing Project (CTSP) to promote the use of genomics in NCI-sponsored clinical trials of the NCTN. Read the March 2015 announcement of the CTSP to NCTN Network Groups.

NCI Cooperative Group Program Archive