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Last Updated: 10/19/16

Investigational Drug Accountability
Training Videos

PMB is pleased to bring you video tutorials that provide detailed step-by-step guidance on various aspects of drug accountability. Each video covers a different function of the NCI Investigational Agent Accountability Record Form, commonly referred to as the Drug Accountability Record Form (DARF). Whether you're learning for the first time or looking for a refresher on a particular topic, take the time right now to learn about investigational drug accountability.

If you are a person with a disability and are having difficulty experiencing the content of these videos, please contact the Pharmaceutical Management Branch (PMB), CTEP/DCTD/NCI/NIH, by telephone 240-276-6575 Monday through Friday from 8:30am to 4:30pm Eastern Time or by emailing PMBAfterHours@mail.nih.gov at any time.

Click here to view the DARF Basics video.

DARF Basics

  • Selection of NCI DARFs
  • Use of eDARFs
  • Corrections on DARFs
  • When separate DARFs are required

DARF Basics Handout (PDF)

Date produced: 09/2014    Length: 05:05

Click here to view the DARF Header video.

DARF Header

  • DARF expiration date
  • Dose Form and Strength descriptors
  • Bottle Size and Local Protocol Number

DARF Header Handout (PDF)

Date produced: 09/2014    Length: 04:33

Click here to view the Oral DARF video.

Oral DARF

  • Agent expiration date
  • Patient returns of multiple lots or empty bottles
  • Multiple patient returns from single dispensing

Oral DARF Handout (PDF)

Date produced: 09/2014    Length: 06:12

Click here to view the Agent Receipt video.

Agent Receipt

  • Agent shipping vs. storage conditions
  • Agent lot identifiers
  • Shipping receipt notes
  • Patient-specific agent lot identifier

Agent Receipt Handout (PDF)

Date produced: 09/2014    Length: 06:03

Click here to view the Agent Dispensing video.

Agent Dispensing

  • Study-eligible investigator checklist
  • Multiple lots or strengths
  • Injectable vial overfill
  • Multi-dose vials

Agent Dispensing Handout (PDF)

Date produced: 06/2015    Length: 09:34

Click here to view the atient-Specific DARFs video.

Patient-Specific DARFs

  • Creating patient-specific DARFs
  • Patient registration and initial shipments
  • Reordering in OAOP
  • Julian dates and inventory management

Patient-Specific DARFs Handout (PDF)

Date produced: 06/2015    Length: 10:14

Click here to view the Agent Transfers video.

Agent Transfers

  • Reasons for transfer request
  • Agent transfer documentation
  • Urgent medical need
  • Transfer request denials

Agent Transfers Handout (PDF)

Date produced: 06/2015     Length: 07:37

Click here to view the Agent Returns video.

Agent Returns

  • Reasons for agent return
  • Agent return documentation
  • Strategies to reduce the need for returns

Agent Returns Handout (PDF)

Date produced: 08/2016     Length: 07:35

Click here to view the Local Destruction video.

Local Destruction

  • Circumstances to request local destruction
  • Local destruction authorization and documentation
  • Reasons for rescission or denial

Local Destruction Handout (PDF)

Date produced: 08/2016     Length: 05:57

About the Branch Chief

Charles Hall, MBA, RPh Mr. Hall received his undergraduate pharmacy degree from the Massachusetts College of Pharmacy in 1975. He was awarded a Master of Science in Business Organizational Management from the University of LaVerne, California in 1991. In 1995, he completed an American Society of Hospital Pharmacy (ASHP) – accredited general pharmacy practice residency at the National Naval Medical Center, Bethesda, Maryland. More…