Create Access to Targeted Cancer Therapy for -Underserved Populations (CATCH-UP.2020)

• Overview/Objectives
• Project Leaders
• Participating Sites
• ETCTN/CATCH-UP.2020 Clinical Trials
• Accomplishments

Overview/Objectives

Create Access to Targeted Cancer Therapy for Underserved Populations (CATCH-UP.2020) is a congressionally mandated P30 administrative supplement award to eight NCI cancer center support grants to enhance access to targeted cancer therapy for minority/underserved populations. The CATCH-UP.2020 initiative is comprised of eight NCI designated cancer centers that demonstrate robust ability to accrue minority/underserved populations to the National Cancer Institute’s Experimental Therapeutics Clinical Trials Network sponsored precision medicine cancer trials but are not members of the ETCTN’s UM1 program. CATCH-UP.2020 cancer centers are required to accrue a minimum of 24 patients annually to NCI ETCTN trials; in which at least 50% of these patients must belong to a minority/underserved population.

CATCH-UP.2020 Project Leaders

CATCH-UP.2020 Participating Sites

Lead Academic Organization

• UC Irvine Health/Chao Family Comprehensive Cancer Center LAO
• University of Alabama at Birmingham Cancer Center LAO
• University of Miami Miller School of Medicine-Sylvester Cancer Center LAO
  • UM Sylvester Comprehensive Cancer Center at Deerfield Beach
  • UM Sylvester Comprehensive Cancer Center at Plantation
  • UM Sylvester Comprehensive Cancer Center at Coral Gables
• Wake Forest University Health Sciences LAO
• Dartmouth-Hitchcock Medical Center/Norris Cotton Cancer Center LAO
  • Norris Cotton Cancer Center-North
• Laura and Isaac Perlmutter Cancer Center at NYU Langone LAO
  • Bellevue Hospital Center
  • NYU Winthrop Hospital
  • NYU Langone Hospital - Brooklyn
• University of Kansas Cancer Center LAO
  • Ascension Via Christi - Pittsburg
  • HaysMed University of Kansas Health System
  • Olathe Health Cancer Center
  • Salina Regional Health Center
  • Truman Medical Centers
  • University of Kansas Cancer Center - Lee's Summit
  • University of Kansas Cancer Center - North
  • University of Kansas Cancer Center at North Kansas City Hospital
  • University of Kansas Cancer Center-Overland Park
  • University of Kansas Clinical Research Center
  • University of Kansas Health System Saint Francis Campus
  • University of Kansas Hospital-Westwood Cancer Center
• Wayne State University/Karmanos Cancer Institute LAO
  • McLaren Cancer Institute-Bay City
  • McLaren Cancer Institute-Flint
  • McLaren-Greater Lansing
  • Weisberg Cancer Treatment Center

*LAO = Lead Academic Organization

ETCTN/CATCH-UP.2020 Clinical Trial Portfolio

CATCH-UP.2020 is a one-time supplement; however, once an administrative supplement is awarded, it is anticipated that collaborations will develop between NCI Cancer Centers, local area providers, public health practitioners, and other public health professionals to utilize an NCI Cancer Center’s infrastructure to open ETCTN trials at their clinical sites, to recruit minority/underserved patients to these ETCTN trials, and to provide resources to maintain participation on ETCTN trials until the patient’s endpoint for the trial is achieved.

For more information on the CATCH-UP.2020 initiative, contact Drs. Steven Gore steven.gore@nih.gov or S. Percy Ivy ivp@ctep.nci.nih.gov.

Accomplishments

Over the course of 18 months, the CATCH-UP.2020 cancer centers accrued a total of 246 patients to NCI ETCTN trials. 127 (52%) of the patients belonged to a federally underserved population. The success of the CATCH-UP.2020 program led to a series of competitive supplements ("Equity-Focused Clinical Investigation Teams") to the ETCTN UM1 grants to continue to enhance diversity, equity, and inclusion efforts in ETCTN sponsored precision medicine cancer trials.